Ohio State kicks off its defense of the national championship with a high-profile showdown against Texas, bringing together what might be the two strongest teams in college football. This clash between the CFP title favorites is shaping up to be a real treat for sports fans, as this Week 1 encounter will significantly influence not just which teams make it to the playoff, but also their positions within the bracket. There’s even a good chance this opening match is a sneak peek at the national title showdown.
In this big game, the Big Ten and SEC square off, representing the two premier conferences in the sport. These conferences are responsible for most of the year’s most anticipated matchups on the 2025 schedule. Meanwhile, the ACC and Big 12 promise thrilling league races with their top teams jostling for playoff spots. However, the teams with the best shot at winning it all are predominantly housed in the more prominent conferences.
Notre Dame is also set to feature in several significant games as they pursue a potential return to the championship game.
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Here’s a look at the top 25 games that are expected to shape the 2025 national championship landscape: