Predicting which underdogs will shake things up in the 2025 NCAA Tournament is always a bit of a gamble, but that’s what makes it exciting. This year is expected to have its fair share of surprises, though pinpointing the specific upsets isn’t simple. For instance, the betting community is eyeing Colorado State for a 12-5 upset. But even if that happens, it might not be the only shocker between Thursday and Friday. If history is any guide, we’ll see plenty of top teams fall and some unexpected ones rise.
FanDuel has rolled out its odds for the First Four and all the initial matchups of the tournament, and some numbers might make you do a double-take. While powerhouses like Florida and Houston are safe bets with the public’s backing, others aren’t shrouded in the same level of confidence.
As we await the outcomes of Tuesday and Wednesday’s games, four teams are in limbo regarding their betting odds. However, once the dust settles, Auburn, Duke, Ole Miss, and Illinois are expected to emerge as favorites for the First Four round.
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Here’s how the odds stack up for each first-round matchup in the 2025 NCAA Tournament:
